Cerebral reflex action.
In a sketch, however brief, of the progress of Psychological Medicine since
the
foundation of this Association in 1841, it would be a serious
omission
not to notice the important contributions of the late Professor Laycock
[1812-1856]
shortly before as well as after that year. In 1840 he first promulgated the
opinion that
"the brain, although [p.469] the organ of consciousness, is
subject to the laws of reflex action, and in this respect does not differ
from other ganglia of the nervous system." (*)
* A Treatise on the Nervous Diseases of Women by Thomas
Laycock, M.D., 1840, chapter 9 p. 107.
And in a paper read before the British Association, September, 1844, he
observed,
"Insanity and dreaming present the best field for investigating
the laws of that extension of action from one portion of the brain to the
other, by which ideas follow each other in sequence, giving as an
illustration the case of a patient at the York Retreat, whose will being
suspended, he expressed ideas as they spontaneously arose in associated
sequence, the combination being singularly varied, but traceable to a
common root or centre of impulse."
"Researches of this kind," Laycock
continues, " whether instituted on the insane, the somnambulist, the
dreamer, or the delirio"us, must be considered like researches in
analytical chemistry. The re-agent is the impression made on the brain ;
the molecular changes following the applications of the reagent are made
known to us as ideas."
British and Foreign Medical Review, January, 1845, p. 311.
Time will not allow me to cite other passages in these remarkable papers,
or later ones ; but these are sufficient to show the germ at that early
period of the doctrine of cerebral reflex action, and the unconscious
cerebration of Carpenter, the seeds having been already sown by Unzer and
Prochaska, and arising out of it, that of automatic states occasioned or
permitted by the abeyance of a higher restraining power - the Will,
[p.470] according to Laycock, in the case he employs as an illustration of
his doctrine. His teaching in regard to mental and nervous disorders due to
vaso-motor disturbance also deserves recognition.
Henry Monro
Dr Henry Monro, again, in a treatise published in 1851, put forward a
theory of the pathology of insanity, the essence of which was that the
cerebral masses having lost their static equilibrium exhibit in their
functions two different degrees of deficient nervous action (coincidently),
viz. irritable excess of action and partial paralysis. He maintained
that these two states do not fall alike upon all the seats of mental
operations, but that there is
" a partial suspension of action " of "
higher faculties, such as reason and will,"
while there is an irritable
excess of action of the seats of the more elementary faculties, such as
conception, etc., and hence delusions and the excessive rapidity of
successive ideas. Dr. Monro compares this condition to a case of
paralysis, combined with convulsions ; and discusses the question whether
the temporary and partial paralysis occurring as he supposes in insanity,
" results directly and entirely from excessive depression of the nervous
centres of those higher faculties, or partly in an indirect manner from
nervous energy being abstracted to other parts which are in more violent
exercise at the time." *
* " Remarks on Insanity, its Nature and Treatment," p. 14.
This, it will be seen, is a still clearer statement of the doctrine that
insanity is caused by the depression or paralysis of the higher nervous
centres and excessive action of others.
p.471
Hughlings Jackson
John Hughlings Jackson was a founder of
Brain
As is well known, Dr Hughlings Jackson, whose views regarding active
states of nerve structures as liberations of energy or discharges, are
familiar to us all, has adopted and extended
Laycock's doctrine, which he
designates as " one of inestimable value," and has urged the importance of
Monro's doctrine of negative and positive states in cases of
insanity,
using the term "insanity" in an exceedingly wide sense.
Adopting the hypothesis of
evolution as enunciated by
Herbert Spencer, Dr Hughlings Jackson thinks
that cases of insanity, and indeed all other nervous diseases, may be
considered as examples of
Dissolution, this being, I need not say, the term
Spencer uses for the process which is the reverse of Evolution.
Insanity, then, according to this view, is dissolution beginning at the
highest cerebral centres, which centres, according to Jackson, represent
or re-represent the whole organism. There are distinguishable, .he
believes, cases of uniform dissolution, the process affecting the highest
centres nearly uniformly, and cases of partial dissolution in which only
some parts of these centres are affected. The dissolution, again,
whether uniform or partial, varies in "depth"; the deeper it is, the
more general are the manifestations remaining possible. The
degree of " depth " of dissolution is, however, but one factor in this
comparative study of insanity.
Another is the rapidity with which it is effected. To this, Dr Jackson
attaches extreme importance, believing that degrees of it account for
degrees of activity of those nervous arrangements next lower than those
hors de combat in the dissolution. Another factor is the kind of
person to
whom dissolution "comes". And the last factor is the influence of
circumstances on the patient undergoing mental dissolution. All factors
should, of course, be considered in each case, or, as Dr Jackson
characteristically puts it,
"insanity is a function of four variables".
I
refer to these opinions to show the direction in which some modern
speculation on the nature of insanity tends, that thus tracing the course
of thought in recent years we may see how, step by step, certain views have
been reached, some of them generally adopted, others regarded as still
requiring proof before they can be accepted.